Statistical Genetics Research at a Major Univsity

The Department of Biostatistics at a major U.S. university conducts research in statistical methodology and applications, as well as in fundamental problems of modeling biomedical systems. Much of this research is performed in collaboration with basic and clinical health scientists within and outside UAB.

Programmers in the Statistical Genetics section of the Department of Biostatistics are using the IMSL Library for Java (JMSL)  for a High Dimensional Biology statistical application. They are analyzing micro-array data using statistical methods from the JMSL Library.

IMSL for Java Helps With...

Greater Developer Productivity

Shorter Development Cycles

Advanced Analytics in 100% Java

Utilizing the JMSL Library redirects the precious time of our software

developers that would otherwise be spent reinventing the wheel. Now the focus can be directed at implementing and refining new and innovative ideas.

Development of New Statistical Techniques

Biostatistics is the field of statistical methods related to biological research in areas such as public health, medicine, agriculture, dentistry, and nursing. The Department of Biostatistics focuses on the application of existing statistical methods to study in these agricultural and health-related fields and the development of new statistical techniques.

The Section Lead was looking for a numerical library to aid in the development of an application for the analysis of HDB data in Statistical Genetics research. The term “HDB” stands for High Dimensional Biology, which is a fairly recent term coined to describe the “omic” sciences that are becoming quite popular areas of research such as genomics, proteomics, etc. The department wanted to concentrate their efforts on writing proprietary algorithms for the application and implementing the novel analysis methods developed by the University into their application.

Due to the fact that they have a small team of programmers, they were looking for an existing, yet highly reliable, solution so they would not have to “reinvent the wheel.” They searched for a sophisticated numerical library that performed the analysis they needed in a quick and efficient way.

A Complete Collection of Mathematical, Statistical, and Charting Classes

A few of the specific traits they were looking for in a numerical library included summary statistics, t-tests, non-linear optimization, random number generation, and PDF’s and CDF’s for common and uncommon distributions. This functionality needed to be in Java to integrate into the application the Biostatistics group was developing. They found the building blocks they required in the IMSL Library for Java (JMSL).

The JMSL Library is a complete collection of mathematical, statistical, and charting classes, written in 100% Java, which provides the ability to develop network-centric, cost-effective data analysis applications. It is the only solution to combine integrated charting with the reliable mathematical and statistical functionality of the industry-leading IMSL Library algorithms.

The team found that the JMSL Library implemented the features necessary to be tremendously useful to his group. JMSL has made it possible to perform simple to complex data analysis on the Java platform by developing a unique set of custom language extensions. These extensions provide the basis for optimized analytics on one of the most flexible and collaborative platforms available. In addition, the JMSL Library provides a strong Java API for its numerical functions.

As a result, the Statistical Genetics group is using the JMSL Library in their application that is used to analyze micro-array data by using known statistical methods as well as novel ones developed within the Section on Statistical Genetics.

Return on Investment

Utilizing the JMSL Library redirects the precious time of our software developers that would otherwise be spent working on accurate and reliable algorithms already present in the Library. Now their focus can be directed at implementing and refining new ideas specific to our work.

The team's level of satisfaction with the JMSL Library is very high. The faster development times combined with shorter development cycles have made their analysis and research in the area Biostatistics much more focused and cost-effective.

As for the technical support team at Perforce, “I couldn’t be happier,” says the lead developer, “The support has been professional and all of my requests and questions have been handled in a very timely manner.”

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